|
|
phytosphingosine + ATP <=> phytosphingosine_1-phosphate + ADP + H+
|
2.7.1.91
sphingosine kinase
|
–
|
M
|
|
BRENDA:
BS378570
MetaCyc:
RXN-20648;
RXN3O-458
|
|
|
|
hexacosanoyl-CoA + phytosphingosine <=> C26:0_phytoceramide + CoA + H+
|
2.3.1.297
very-long-chain ceramide synthase
|
–
|
|
|
BRENDA:
BS435520
MetaCyc:
RXN-20398
|
|
|
|
lignoceroyl-CoA + phytosphingosine <=> N-lignoceroylphytosphinganine + CoA + H+
|
2.3.1.297
very-long-chain ceramide synthase
|
–
|
|
|
BRENDA:
BS448738
MetaCyc:
RXN-20399
|
|
|
|
phytoceramide + H2O <=> phytosphingosine + fatty_acid
|
3.5.1.23
ceramidase
|
–
|
K
|
|
BRENDA:
BS413533
KEGG:
R06528
|
|
|
|
sphinganine + O2 + ferricytochrome_b5 + H+ <=> phytosphingosine + H2O + ferricytochrome_b5
|
1.14.18.5
sphingolipid C4-monooxygenase
|
–
|
MK
|
|
KEGG:
R06525
MetaCyc:
RXN3O-1380
|
|
|
|
acyl-CoA + phytosphingosine <=> CoA + phytoceramide
|
2.3.1.24
sphingosine N-acyltransferase
|
–
|
K
|
|
KEGG:
R06527
|
|
|
|
very-long-chain_(2''R)-2''-hydroxy-phytoceramide + H2O <=> phytosphingosine + very-long-chain_(2R)-2-hydroxy_fatty_acid
|
3.5.1.23
ceramidase
|
–
|
M
|
|
MetaCyc:
CERAMIDASE-YEAST-RXN
|
|
|
|
30-hydroxytriacontanoyl-CoA + phytosphingosine <=> N-(30-hydroxytriacontanoyl)-phytosphingosine + CoA + H+
|
2.3.1.298
ultra-long-chain ceramide synthase
|
–
|
M
|
|
MetaCyc:
RXN-20360
|
|
|
|
(2''R)-2''-hydroxy-phytoceramide + H2O <=> phytosphingosine + (2R)-2-hydroxy_even_numbered_straight_chain_2,3,4-saturated_fatty_acid
|
3.5.1.23
ceramidase
|
–
|
M
|
|
MetaCyc:
RXN-20504
|
|
|
|
behenoyl-CoA + phytosphingosine <=> very-long-chain_phytoceramide + CoA + H+
|
2.3.1.297
very-long-chain ceramide synthase
|
–
|
M
|
|
MetaCyc:
RXN3O-328
|
|
|
|
phytosphingosine_1-phosphate + H2O <=> phytosphingosine + phosphate
|
3.1.3
|
–
|
M
|
|
MetaCyc:
RXN3O-504
|
|
|
|
N-dodecanoyl-7-nitrobenz-2-oxa-1,3,4-diazole-D-erythro-dihydrosphingosine + H2O <=> 12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanate + phytosphingosine
|
3.5.1.23
ceramidase
|
–
|
|
|
BRENDA:
BS414948
|
|
|
|
11-eicosenoyl-dihydroceramide + H2O <=> phytosphingosine + 11-eicosenoic_acid
|
3.5.1.23
ceramidase
|
–
|
|
|
BRENDA:
BS413848
|
|
|
|
an_ultra-long-chain_fatty_acyl-CoA + phytosphingosine <=> phytoceramide + CoA
|
2.3.1.298
ultra-long-chain ceramide synthase
|
–
|
|
|
BRENDA:
BS448442
|
|
|
|
a_fatty_acyl-CoA + phytosphingosine <=> CoA + an_N-acylphytosphingosine
|
2.3.1.24
sphingosine N-acyltransferase
|
–
|
|
|
BRENDA:
BS455137
|
|
|
|
N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]lauroyl]-phytosphingosine + H2O <=> N-12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]laurate + phytosphingosine
|
3.5.1.23
ceramidase
|
–
|
|
|
BRENDA:
BS414999
|
|
|
|
N-arachidonoyl-dihydroceramide + H2O <=> phytosphingosine + arachidonic_acid
|
3.5.1.23
ceramidase
|
–
|
|
|
BRENDA:
BS414931
|
|
|
|
N-oleoyl-phytoceramide + H2O <=> phytosphingosine + oleic_acid
|
3.5.1.23
ceramidase
|
–
|
|
|
BRENDA:
BS414987
|
|
|
|
sphinganine + NADH + H+ + O2 <=> phytosphingosine + NAD+ + H2O
|
1.14.18.5
sphingolipid C4-monooxygenase
|
–
|
|
|
BRENDA:
BS433607
|
|
|
|
acyl-CoA + phytosphingosine <=> CoA + N-acylphytosphingosine
|
2.3.1.24
sphingosine N-acyltransferase
|
–
|
|
|
BRENDA:
BS455266
|
|
|
|
stearoyl-CoA + phytosphingosine <=> CoA + phytoceramide
|
2.3.1.24
sphingosine N-acyltransferase
|
–
|
|
|
BRENDA:
BS456704
|
|
|
|
sphinganine + NADPH + H+ + O2 <=> phytosphingosine + NADP+ + H2O
|
1.14.18.5
sphingolipid C4-monooxygenase
|
–
|
|
|
BRENDA:
BS433608
|
|
|
|
sphingosine + reduced_acceptor + H+ + O2 <=> phytosphingosine + acceptor + H2O
|
1.14.18.5
sphingolipid C4-monooxygenase
|
–
|
|
|
BRENDA:
BS421520
|
|
|
|
D(+)erythro-sphinganine + reduced_acceptor + H+ + O2 <=> phytosphingosine + acceptor + H2O
|
1.14.18.5
sphingolipid C4-monooxygenase
|
–
|
|
|
BRENDA:
BS420619
|
|
|
|
phytosphingosine + reduced_acceptor + H2O <=> 4-hydroxy-trans-8-sphingenine + acceptor + H2O
|
1.14.19.4
acyl-lipid (11-3)-desaturase
|
–
|
|
|
BRENDA:
BS375892
|
|
|
|
phytosphingosine + ferricytochrome_b5 + O2 + H+ <=> C18-8-phytosphingenine + ferricytochrome_b5 + H2O
|
1.14.19.29
sphingolipid 8-(E/Z)-desaturase
|
–
|
|
|
BRENDA:
BS432720
|
|
|
|
phytosphingosine + ferricytochrome_b5 + O2 + H+ <=> (4R,8Z)-4-hydroxy-8-sphingenine + 4-hydroxy-trans-8-sphingenine + ferricytochrome_b5 + H2O
|
1.14.19.18
sphingolipid 8-(E)-desaturase
|
–
|
|
|
BRENDA:
BS433531
|
|
|
|
phytosphingosine + ferricytochrome_b5 + O2 + H+ <=> 4-hydroxy-trans-8-sphingenine + ferricytochrome_b5 + H2O
|
1.14.19.18
sphingolipid 8-(E)-desaturase
|
–
|
|
|
BRENDA:
BS433284
|
|